Tim Mercer

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Tim completed his BSc (hons) at the University of Western Australia and the Western Australian Institute for Medical Research. He completed his PhD in the Mattick laboratory in 2008 with the thesis topic "The expression of long noncoding RNAs in development and differentiation".

His major research interests are with the annotation and functional characterization of long noncoding RNAs and their contribution towards disease aetiology.

He also regularly updates and helps to maintain the long noncoding RNA entry in the Wikipedia.

Email: t.mercer@garvan.org.au

Publications

Dinger ME, Amaral PP, Mercer TR, Mattick JS. Pervasive transcription of the eukaryotic genome: functional indices and conceptual implications. Brief Funct Genomic Proteomic. Preprint.

Pang KC, Dinger ME, Mercer TR, Malquori L, Grimmond SM, Chan W, Mattick JS (2009). Genome-wide identification of long noncoding RNAs in CD8+ T cells. J Immunol. 182: 7738-7748.

Mercer TR, Dinger ME, Mattick JS (2009). Long noncoding RNAs: insights into function. Nature Rev Genet. 10: 155-159.

Dinger ME, Pang KC, Mercer TR, Crowe ML, Grimmond SM, Mattick JS (2009). NRED: a database of long noncoding RNA expression. Nucleic Acid Res 37: D122-6.

Mattick JS, Amaral PP, Dinger ME, Mercer TR, Mehler MF (2009). RNA regulation of epigenetic processes. Bioessays. 31: 51-59.

Mercer TR, Dinger ME, Mariani J, Kosik KS, Mehler MF, Mattick JS (2008). Noncoding RNAs in long-term memory formation. Neuroscientist. 14: 434-445.

Dinger ME, Pang KC, Mercer TR, Mattick JS (2008). Differentiating protein-coding and noncoding RNA: challenges and ambiguities. PLoS Comp Biol 4: e1000176.

Dinger ME*, Amaral PP*, Mercer TR*, Pang KC, Bruce SJ, Gardiner BB, Askarian-Amiri ME, Ru K, Soldà G, Simons C, Sunkin SM, Crowe ML, Grimmond SM, Perkins AC, Mattick JS (2008). Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation. Genome Res 18: 1433-1445.

Mercer TR*, Dinger ME*, Mariani J, Kosik KS, Mehler MF, Mattick JS (2008). Non-coding RNAs in long-term memory formation. Neuroscientist TBA: in press.

Amaral PP, Dinger ME, Mercer TR, Mattick JS (2008). The eukaryotic genome as an RNA machine. Science 319: 1787-1789.

Dinger ME*, Mercer TR*, Mattick JS (2008). RNAs as extracellular signaling molecules. J Mol Endocrinol 40: 151-159.

Mercer TR*, Dinger ME*, Sunkin SM, Mehler MF, Mattick JS (2008). Specific expression of long noncoding RNAs in the adult mouse brain. Proc Natl Acad Sci USA 105: 716-721.

Wu H, Boackle SA, Hanvivadhanakul P, Ulgiati D, Grossman JM, Lee Y, Shen N, Abraham LJ, Mercer TR, Park E, Hebert LA, Rovin BH, Birmingham DJ, Chang DM, Chen CJ, McCurdy D, Badsha HM, Thong BY, Chng HH, Arnett FC, Wallace DJ, Yu CY, Hahn BH, Cantor RM, Tsao BP (2007) Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus. Proc Natl Acad Sci USA 104: 3961-6.

  • these authors contributed equally towards this work
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